Search results for "Cellulose acetate"

showing 7 items of 7 documents

Multicomponent solid dispersion as a formulation strategy to improve drug permeation: A case study on the anti-colorectal cancer irinotecan

2019

Abstract Multicomponent solid dispersions (MSD)s are frequently proposed as efficient drug delivery systems to improve drug solubility and bioavailability. In this study, the effects of specific excipients, such as mannitol, inulin, poly(methyl methacrylate-co-methacrylic)acid (PMMA) and cellulose acetate phthalate (CAP) have been tested to potentially improve irinotecan (IRN) permeation in the intestinal tract with the intention to protect the drug from the gastric environment. MSDs were formulated as microparticles by Spray-Drying technique. Raw materials and microparticles have been characterized by FTIR analysis to determine hydrogen bonding. SEM images were recorded to investigate morp…

ChromatographyPharmaceutical Science02 engineering and technologyPermeation021001 nanoscience & nanotechnology030226 pharmacology & pharmacyBioavailabilityMulticomponent solid dispersion Microparticles Irinotecan Inulin Spray-drying03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCellulose acetate phthalatechemistrySettore CHIM/09 - Farmaceutico Tecnologico ApplicativoDrug deliveryDissolution testingParticle sizeSolubility0210 nano-technologyDissolutionJournal of Drug Delivery Science and Technology
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Nachweis von fetalem H�moglobin in Blutspuren mit Hilfe der Celluloseacetatfolien- (CAF) -Elektrophorese

1977

Blutspuren von 160 Nabelvenenblutproben wurden elektrophoretisch nach der von Wraxall beschriebenen Technik aufgetrennt und konnten gut drei Monate lang nach Lagerung bei Zimmertemperatur von Erwachsenenblutspuren unterschieden werden. Unterschiedliche Spurentrager (Glas, Holz, Filterpapier und Leinen) hatten keinen nennenswerten Einflus auf die Darstellung.

Electrophoresischemistry.chemical_compoundChromatographyChemistryAnatomyCellulose acetatePathology and Forensic MedicineZeitschrift f�r Rechtsmedizin
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Effective Degradation of Cigarette Butts via Treatment with Old Landfill Leachates

2021

In this paper, results of feasibility study on microplastics (MPs) assessment in leachates from the Latvian solid municipal landfill Getliņi are discussed. The application of leachates for the treatment of cigarette butts (CGB) was evaluated. Methods of fluorescent microscopy, Fourier transform infrared (FTIR) spectroscopy and FTIR-microscopy were used for the identification and characterization of MPs in the leachates and analysis of CGB. Presence of the secondary MPs (e.g., degraded polyolefin mixtures) was determined in the tested landfill leachates, while cellulose acetate (CA) was not determined in these products. The leachates were tested as potential media for the thermophilic (55°C)…

Microplastics010504 meteorology & atmospheric sciencesChemistryMechanical Engineering010501 environmental sciencesBiodegradation01 natural sciencesCellulose acetatechemistry.chemical_compoundMechanics of MaterialsEnvironmental chemistryDegradation (geology)General Materials ScienceLeachateFourier transform infrared spectroscopy0105 earth and related environmental sciencesKey Engineering Materials
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Fractionation of cellulose acetate for the investigation of molecular weight influences on the morphology of membranes

2003

Abstract Cellulose acetate (CA) with an apparent weight average molar mass, M w ∗ , of 150 kg/mol was fractionated with respect to M by means of the mixed solvent methyl acetate (MeAc)/2-propanol (2-POH) applying a new method that uses spinning nozzles to promote the rapid attainment of phase equilibria. Two of the fractions obtained in this manner were employed to prepare membranes from solutions in methyl acetate with 2-propanol as coagulating agent. Electron micrographs demonstrate that the molar mass of CA influences the morphology of the membranes markedly under otherwise identical conditions. For M w ∗ =128  kg/mol, one obtains considerably denser structures than for M w ∗ =263  kg/mo…

Molar massChemistryMethyl acetateMembrane structureFiltration and SeparationFractionationBiochemistryCellulose acetateSolventchemistry.chemical_compoundMembranePhase (matter)Polymer chemistryGeneral Materials SciencePhysical and Theoretical ChemistryNuclear chemistryJournal of Membrane Science
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ZnO/polyaniline composite based photoluminescence sensor for the determination of acetic acid vapor

2020

In this study, we report a novel ZnO/polyaniline (PANI) nanocomposite optical gas sensor for the determination of acetic acid at room temperatures. ZnO nanorods, synthesized in powder form were coated by PANI (ZnO/ PANI) by chemical polymerization method. The obtained nanocomposites were deposited on glass substrate and dried overnight at room temperature. Structure and optical properties of ZnO/PANI nanocomposite have been studied by using X-ray diffraction, transmission electron microscopy, scanning electron microscopy, diffuse reflectance and photoluminescence spectroscopy. Tests towards acetic acids were performed in the range of concentrations 1–13 ppm. The adsorption of acetic a…

PhotoluminescenceConducting polymers02 engineering and technologyAcetic acid01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundAcetic acidCellulose degradationPolyanilinePhotoluminescenceConductive polymerNanocomposite010401 analytical chemistry021001 nanoscience & nanotechnologyCellulose acetateZnO-PANI composite0104 chemical sciencesChemical engineeringchemistry:NATURAL SCIENCES [Research Subject Categories]Light emissionNanorodGas sensor0210 nano-technologyTalanta
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Formation of micro- and nano-spheric particles (filter dust) during the preparation of cellulose acetate membranes

2003

Abstract Membranes were prepared from six samples of cellulose acetate (CA) differing in their average molecular weight (75–260 kg/mole) and molecular weight distribution using methyl acetate as solvent and 2-propanole as precipitant. The routes through the phase diagram and the evaporation times were varied in these experiments. Electron microscopy demonstrates that the amount of filter dust (CA particles deposited on the membrane surface) decreases as the fraction of low molecular weight material in the starting polymer becomes less. For low average molar mass of CA and moderate polymer concentrations in the casting solution the dust consists of individual spheres of relatively uniform si…

chemistry.chemical_classificationMolar massMaterials scienceMethyl acetateEvaporationFiltration and SeparationPolymerBiochemistryCastingCellulose acetatechemistry.chemical_compoundMembranechemistryChemical engineeringPolymer chemistryMolar mass distributionGeneral Materials SciencePhysical and Theoretical ChemistryJournal of Membrane Science
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Muscle adenylate kinase in Duchenne muscular dystrophy

1986

Abstract On the basis of electrophoretic and enzyme inhibition studies it was postulated that an aberrant adenylate kinase occurs in muscle and serum of patients with Duchenne muscular dystrophy (Schirmer, R.H. and Thuma, E. (1972) Biochim. Biophys. Acta 268, 92–97; Hamada, M. et al. (1981) Biochim. Biophys. Acta 660, 227–237; Hamada et al. (1985) J. Biol. Chem. 260, 11595–11602. On the basis of the following results we conclude that Duchenne muscular dystrophy patients do not possess an unusual adenylate kinase isoenzyme. (1) In muscle biopsies from five Duchenne patients, the electrophoretic mobility of adenylate kinase and the inhibition of the enzyme by P 1 , P 5 -di(adenosine-5′)pentap…

medicine.medical_specialtyDTNBDuchenne muscular dystrophyBiophysicsAdenylate kinaseDithionitrobenzoic AcidBiochemistryIsozymeMuscular Dystrophieschemistry.chemical_compoundNormal muscleInternal medicinemedicineHumansheterocyclic compoundsSulfhydryl CompoundsMolecular Biologychemistry.chemical_classificationAdenine NucleotidesMusclesAdenylate KinasePhosphotransferasesElectrophoresis Cellulose Acetatemedicine.diseaseMOPSIsoenzymesEndocrinologyEnzymechemistryPMSFDinucleoside PhosphatesBiochimica et Biophysica Acta (BBA) - General Subjects
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